TTANGO aims to take the next key steps towards wider implementation of STI POC testing in high prevalence areas in Australia. Through TTANGO, STI POC testing for chlamydia, gonorrhoea and trichomonas on the Cepheid GeneXpert® is being implemented in a network of primary health services in regional and remote Australian communities. POC testing has lead to better control of STIs with improved health outcomes for Aboriginal and Torres Strait Islander people, and national adoption of the POC test in similar settings.